Capture and Visualization of Hydrogen Sulfide by a Fluorescent Probe

A selective colorimetric and ratiometric fluorescent probe for hydrogen sulfide.

A reaction-based colorimetric and ratiometric fluorescent probe based on an ICT-strategy for selective detection of H(2)S that exploited the H(2)S-mediated reduction of nitrocompound to amines was explored. And it displayed high selectivity for H(2)S over other relevant reactive sulfur, oxygen, nitrogen species and other anions with more than 120 nm blue shift and the change of emission intensi...

Hydrogen sulfide and resolution of acute inflammation: A comparative study utilizing a novel fluorescent probe

Hydrogen sulfide is an essential gasotransmitter associated with numerous pathologies. We assert that hydrogen sulfide plays an important role in regulating macrophage function in response to subsequent inflammatory stimuli, promoting clearance of leukocyte infiltrate and reducing TNF-α levels in vivo following zymosan-challenge. We describe two distinct methods of measuring leukocyte hydrogen ...

A fluorescent probe for fast and quantitative detection of hydrogen sulfide in blood.

Imaging of living cells and zebrafish in vivo using a ratiometric fluorescent probe for hydrogen sulfide.

We have developed a novel colorimetric and ratiometric fluorescence probe for the selective and sensitive monitoring of hydrogen sulfide based on a dicyanoisophorone platform. An excellent linear relationship of fluorescence intensity ratio (I637/I558) (R(2) = 0.9867) versus hydrogen sulfide concentration in the range of 1-12 μM was obtained. This probe exhibited a remarkable fluorescence respo...

A highly selective fluorescent probe for quantitative detection of hydrogen sulfide.

We designed and synthesized a highly selective and sensitive fluorescent probe for hydrogen sulfide (H2S) based on the one step nucleophilic addition reaction between H2S and electron-poor C=C double bond. Our proposed probe displayed high selectivity for H2S over other analytes including cysteine (Cys) and glutathione (GSH), which might be because the steric hindrance of H2S is less than other...